Antidiarrheal and antispasmodic activities of <i>Vitex negundo</i> are mediated through calcium channel blockade
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منابع مشابه
Antispasmodic and Antidiarrheal Activities of Valeriana hardwickii Wall. Rhizome Are Putatively Mediated through Calcium Channel Blockade
Valeriana hardwickii is indigenous to Pakistan, Burma and Ceylon, where it is traditionally being used as an antispasmodic and antidiarrheal, besides its culinary use as spice. The aim of this paper was to provide pharmacological validation to these medicinal uses. The crude aqueous-methanolic extract of Valeriana hardwickii rhizome (Vh.Cr) was studied on isolated rabbit jejunum and castor oil-...
متن کاملAntidiarrheal and antispasmodic activities of Salvia officinalis are mediated through activation of K channels
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متن کاملAntispasmodic and bronchodilator activities of Artemisia vulgaris are mediated through dual blockade of muscarinic receptors and calcium influx.
AIM OF THE STUDY The present study describes antispasmodic, antidiarrheal, bronchodilatory and tracheo-relaxant activities of Artemisia vulgaris to rationalize some of its traditional uses. MATERIALS AND METHODS Crude extract of Artemisia vulgaris (Av.Cr) was studied in the isolated tissue preparations of rabbit jejunum and guinea-pig trachea, as well as in the in vivo castor oil-induced diar...
متن کاملAntispasmodic and vasodilator activities of Morinda citrifolia root extract are mediated through blockade of voltage dependent calcium channels
BACKGROUND Morinda citrifolia (Noni) is an edible plant with wide range of medicinal uses. It occurs exclusively in tropical climate zone from India through Southeast Asia and Australia to Eastern Polynesia and Hawaii. The objective of this study was to explore the possible mode(s) of action for its antispasmodic, vasodilator and cardio-suppressant effects to rationalize its medicinal use in gu...
متن کاملThe antidiarrheal and spasmolytic activities of Phyllanthus emblica are mediated through dual blockade of muscarinic receptors and Ca2+ channels.
AIM OF THE STUDY This study was aimed at providing the possible mechanisms for the medicinal use of Phyllanthus emblica in diarrhea. MATERIALS AND METHODS The in vivo studies were conducted in mice, while isolated rabbit jejunum and guinea-pig ileum were used for the in vitro experiments. RESULTS The crude extract of Phyllanthus emblica (Pe.Cr), which tested positive for alkaloids, tannins,...
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ژورنال
عنوان ژورنال: Bangladesh Journal of Pharmacology
سال: 2013
ISSN: 1991-0088,1991-007X
DOI: 10.3329/bjp.v8i3.15296